Medicine Sick Day Rules

What to do when you are unwell

When you are unwell certain medications should be temporarily stopped to prevent serious complications e.g. dehydration, kidney issues or diabetes complications

These are the Medicine Sick Day Rules if you have:

  • Vomiting or diarrhoea (for more than 24 hours)
  • A high fever, sweats, or shaking (signs of infection)
  • Dehydration (not drinking normally or passing minimal or very dark urine)

Which Medicines Should Be Stopped?

You should temporarily stop taking certain medications until you are well again:

SGLT2 inhibitors

What are SGLT2 inhibitors

Use

Diabetes, Kidney, Heart conditions

Examples

Empagliflozin, Dapagliflozin, Canagliflozin

ACE inhibitors

What are ACE inhibitors

Use

Blood pressure, Heart conditions

Examples

Ramipril, Lisinopril, Enalapril

Diuretics

What are Diuretics

Use

“Water tablets”, Fluid retention, Blood pressure

Examples

Furosemide, Bendroflumethiazide, Spironolactone, Indapamide

Metformin

What is Metformin

Use

Diabetes

ARBs

What are ARBs

Use

Blood pressure, Heart condition

Examples

Losartan, Candesartan, Valsartan

NSAIDs

What are NSAIDs

Use

Anti-inflammatory pain killers

Examples

Ibuprofen, Naproxen, Diclofenac

Sulfonylureas

What are Sulfonylureas

Use

Diabetes

Examples

Gliclazide, Glimepiride

What Should You Do?

  1. Continue drinking fluids – regular small sips of water.
  2. Monitor your urine output – if you are not passing urine or it is very dark, seek urgent review
  3. Monitor your blood sugar levels if you have diabetes.
  4. You can take paracetamol for pain relief or high temperature
  5. Contact your GP, pharmacist, or NHS 111 if you are concerned.
  6. Restart medicines once you are well again i.e. eating and drinking normally for 24-48 hours - unless advised otherwise.

When to Seek Urgent Help

Seek medical attention if:

  • You cannot keep fluids down
  • You are passing no urine for 12 hours or more
  • You feel dizzy or confused
  • You have severe abdominal pain or persistent vomiting
  • You are not improving after 48 hours

Further Information

For advice contact your GP, pharmacist, or NHS 111